Registered Nurse Jobs in Sioux Falls, SD

138 live registered nurse jobs in Sioux Falls, SD, updated daily from hospitals and health systems. Every listing links to the employer's own application, or you can apply with Betterleap and chat with a recruiter.

1. Registered Nurse (RN) | Hematology and Transplant Cellular Therapy Infusion — Avera Health · Sioux Falls, SD · Full-time
2. RN Triage - Registered Nurse - 34th & Kiwanis Family Medicine Clinic - FT Days — Sanford Health · Sioux Falls, SD · Full-time
3. RN Triage - Registered Nurse - 69th & Minnesota Family Medicine Clinic - FT Days — Sanford Health · Sioux Falls, SD · Full-time
4. Registered Nurse (RN) Case Manager | Avera Health Plans Medical Management — Avera Health · Sioux Falls, SD · Full-time
5. Registered Nurse | Behavioral Health | EC Therapy — Avera Health · Sioux Falls, SD · Part-time
6. RN - Registered Nurse - Orthopedics & Neurology - Rotating — Sanford Health · Sioux Falls, SD · Full-time
7. RN - Registered Nurse - Surgical Renal & Transplant Unit - Part Time — Sanford Health · Sioux Falls, SD · Part-time
8. Registered Nurse (RN) - New Grad - December 2026 — Avera Health · Sioux Falls, SD · Full-time
9. Registered Nurse (RN) Patient Care Coordinator | Avera at Home Hospice and Home Health — Avera Health · Sioux Falls, SD · Full-time
10. RN - Registered Nurse - Hospital Outpatient Scheduling - Patient Appointment Center — Sanford Health · Sioux Falls, SD · Full-time
11. RN - Registered Nurse - Clinical Call Center — Sanford Health · Sioux Falls, SD · Full-time
12. Registered Nurse (RN) - New Grad - May 2027 — Avera Health · Sioux Falls, SD · Full-time
13. Registered Nurse (RN) Case Manager — Avera Health · Sioux Falls, SD · Full-time
14. RN - Registered Nurse - Clinical Call Center - Straight Nights, Straight Weekends — Sanford Health · Sioux Falls, SD · Full-time
15. Registered Nurse - RN - Vascular Clinic — Sanford Health · Sioux Falls, SD · Full-time
16. Registered Nurse (RN) Case Manager | Avera at Home — Avera Health · Sioux Falls, SD · Full-time
17. Registered Nurse (RN) | Behavioral Health Addiction Adolescent Unit — Avera Health · Sioux Falls, SD · Full-time
18. Registered Nurse - Cardiology & Cardiac Specialty Unit - Nights — Sanford Health · Sioux Falls, SD · Full-time
19. RN - Registered Nurse - Children's Float Pool - Straight Nights — Sanford Health · Sioux Falls, SD · Full-time
20. Registered Nurse (RN) | Postpartum | GYN — Avera Health · Sioux Falls, SD · Full-time