Registered Nurse Jobs in South Dakota

554 live registered nurse jobs in South Dakota, updated daily from hospitals and health systems. Every listing links to the employer's own application, or you can apply with Betterleap and chat with a recruiter.

1. RN | ICU, Monument Health · Rapid City, SD · Full-time
2. RN Traveler- Medical Cardiopulmonary/Pulmonary Acute, Sanford Health · Sioux Falls, SD · Full-time
3. RN - Registered Nurse - Medical Cardiopulmonary & Pulmonary Acute - Weekend Days, Sanford Health · Sioux Falls, SD · Full-time
4. RN New Grad December 2026, Avera Health · Sioux Falls, SD · Full-time
5. Registered Nurse (RN) | Freeman Regional Hospital, Avera Health · Freeman, SD · Full-time
6. RN | ICU, Monument Health · Rapid City, SD · Part-time
7. RN | Float Pool, Monument Health · Rapid City, SD · Part-time
8. RN Traveler-Medical Cardiopulmonary/Pulmonary Acute, Sanford Health · Sioux Falls, SD · Full-time
9. RN Traveler -Ortho/Neuro, Sanford Health · Sioux Falls, SD · Full-time
10. RN - Inpatient Mixed Acuity, Avera Health · Sioux Falls, SD · Full-time
11. Registered Nurse (RN - III) | Emergency Department, Avera Health · Sioux Falls, SD · Full-time
12. RN PreOp/Recovery | Endoscopy, Monument Health · Rapid City, SD · Full-time
13. RN | Float Pool, Monument Health · Rapid City, SD · Full-time
14. Manager, RN Inpatient - OR - Full Time, Sanford Health · Sioux Falls, SD · Full-time
15. RN Traveler -Central Resource Pool, Sanford Health · Sioux Falls, SD · Full-time
16. Supervisor - Registered Nurse | Behavioral Health Senior Unit, Avera Health · Sioux Falls, SD · Full-time
17. Registered Nurse (RN) | Dialysis, Avera Health · Sioux Falls, SD · Full-time
18. RN | Recovery Room, Monument Health · Rapid City, SD · Part-time
19. RN | Ortho/Neuro/Surgical, Monument Health · Rapid City, SD · Part-time
20. RN Traveler- Medical Cardiopulmonary/Pulmonary Acute, Sanford Health · Sioux Falls, SD · Full-time