Registered Nurse Jobs in South Carolina

1,276 live registered nurse jobs in South Carolina, updated daily from hospitals and health systems. Every listing links to the employer's own application, or you can apply with Betterleap and chat with a recruiter.

1. Registered Nurse (RN) - Surgical Care Unit (SCU) - Berkeley Hospital — Bon Secours Mercy Health · Summerville, SC · Full-time
2. Staff Nurse (FT) Medical Surgical — McLeod Health · Little River, SC
3. Registered Nurse (RN) - Post Anesthesia Care Unit (PACU) - St. Francis Downtown — Bon Secours Mercy Health · Greenville, SC · Full-time
4. Registered Nurse - Weekend Intake — Universal Health Services · West Columbia, SC · Full-time
5. Registered Nurse - Maternity — Conway Medical Center · Conway, SC · Full-time
6. Registered Nurse - Per Diem — Ernest Health · Cayce, SC · PRN
7. Home Health Baylor Registered Nurse — Humana Medical Group Inc · Columbia, SC · $77k–$106k/yr · Full-time
8. Registered Nurse - Full-time (Nights) — Ernest Health · Greenwood, SC · Full-time
9. RN - Postpartum — Universal Health Services · Aiken, SC · PRN
10. Registered Nurse - in-Patient Surgical Unit — Conway Medical Center · Conway, SC · Full-time
11. Registered Nurse- Emergency Department — Novant Health · Mount Pleasant, SC
12. RN Medical ICU — Novant Health · Hardeeville, SC · Part-time
13. Hospital Dialysis Registered Nurse — Davita Inc · Greenwood, SC · Full-time
14. Staff Nurse - Weekend — AnMed Health · Anderson, SC · Part-time
15. Staff Nurse - Weekend — AnMed Health · Anderson, SC · Part-time
16. Hospital Dialysis Registered Nurse - Upstate Float — Davita Inc · Spartanburg, SC · Full-time
17. Clinical Care Nurse (RN) — Humana Medical Group Inc · North Charleston, SC · $71k–$98k/yr · Full-time
18. Fall 2026 New Graduate RN Phoebe Sumter — Phoebe Putney Health Systems · Sumter, SC · Full-time
19. Registered Nurse CCU FT Nights — Phoebe Putney Health Systems · Sumter, SC · Full-time
20. Dialysis RN — Encompass Health · Irmo, SC · Full-time