Registered Nurse Jobs in South Carolina

1,177 live registered nurse jobs in South Carolina, updated daily from hospitals and health systems. Every listing links to the employer's own application, or you can apply with Betterleap and chat with a recruiter.

1. Registered Nurse (RN)-Renal Metabolic Acute Care Telemetry-PRN Tier II-NIGHTS, Spartanburg Regional Healthcare System · Spartanburg, SC · PRN
2. Internal Agency- Registered Nurse, McLeod Health · SC · $50+/hr
3. Registered Nurse - Operating Room - FT / Cnor & Fa Required, McLeod Health · Florence, SC
4. Oncology Nurse Navigator - Endocrine, Medical University of South Carolina Medical Center · Charleston, SC · Full-time
5. Registered Nurse - Children's Health - MUSCP, Medical University of South Carolina Medical Center · Charleston, SC · Full-time
6. Registered Nurse (RN) – Med Surg – Roper Hospital – 6 South, Bon Secours Mercy Health · Charleston, SC · Full-time
7. Registered Nurse (RN) - Hospice - Multiple Locations, Bon Secours Mercy Health · Ladson, SC · Full-time
8. RN Endoscopy PRN, Spartanburg Regional Healthcare System · Spartanburg, SC · PRN
9. Registered Nurse (RN)-Med Surg MB-PRN Tier II-NIGHTS, Spartanburg Regional Healthcare System · Spartanburg, SC · PRN
10. RN New Graduate 2026 Loris, McLeod Health · Loris, SC
11. RN New Graduate 2026 Seacoast, McLeod Health · Little River, SC
12. Registered Nurse I - Children's After Hours and Specialty Clinic (North Charleston), Medical University of South Carolina Medical Center · North Charleston, SC · Part-time
13. Obstetric (OB) Triage RN- FT Womens Services, Medical University of South Carolina Medical Center · Florence, SC · Full-time
14. Registered Nurse (RN) - Hospice - Multiple Locations, Bon Secours Mercy Health · Ladson, SC · Full-time
15. New Grad - Registered Nurse (RN) – Med-Surg – St. Francis Downtown, Bon Secours Mercy Health · Greenville, SC · Full-time
16. PRN Registered Nurse-Tier 2- Plastics/Reconstructive Surgery/ 6 tower, Spartanburg Regional Healthcare System · Spartanburg, SC · PRN
17. Staffing Response Team-Level 1-Med Surg/Tele (RN), Spartanburg Regional Healthcare System · Spartanburg, SC · Full-time
18. New Graduate RN - McLeod Dillon, Cheraw, and Clarendon campuses, McLeod Health · Dillon, SC
19. RN Adult/Pediatric Infusion Float- Charleston Outpatient Clinics, Medical University of South Carolina Medical Center · Charleston, SC · Full-time
20. Registered Nurse II - SJCH Peds ER, Medical University of South Carolina Medical Center · Charleston, SC · Full-time