Registered Nurse Jobs in South Carolina

1,177 live registered nurse jobs in South Carolina, updated daily from hospitals and health systems. Every listing links to the employer's own application, or you can apply with Betterleap and chat with a recruiter.

1. Student Nurse Associate- December 2026, Spartanburg Regional Healthcare System · Spartanburg, SC · PRN
2. Occupational Health Nurse - Industry - PRN, As Needed, McLeod Health · SC · PRN
3. Physician Office - RN - McLeod Pulmonology & Critical Care Associates Florence Pbc - Mrmc, McLeod Health · SC
4. Registered Nurse I & II - 7W Surgical Oncology, Medical University of South Carolina Medical Center · Charleston, SC · Full-time
5. Charleston Outpatient Float- RN Pediatric and Adult Infusion, Medical University of South Carolina Medical Center · Charleston, SC · Full-time
6. Registered Nurse (RN) - Med Surg Unit - St. Francis Eastside, Bon Secours Mercy Health · Greenville, SC · Full-time
7. Registered Nurse (RN) - Home Health - Per Visit - Multiple Locations, Bon Secours Mercy Health · Ladson, SC · Full-time
8. Registered Nurse (RN) - Min Data Set (MDS) Coordinator - PRN - Skilled Nursing - Woodruff Manor, Spartanburg Regional Healthcare System · Woodruff, SC · PRN
9. Registered Nurse (RN) - Home Health, Spartanburg Regional Healthcare System · Spartanburg, SC · Full-time
10. RN, PRN, Share the Care, Cheraw, McLeod Health · Cheraw, SC · PRN
11. Registered Nurse -PRN (As Needed) Home Health (Various Locations), McLeod Health · SC · PRN
12. Registered Nurse (RN) MUSC Florence Recovery Room - FT, Medical University of South Carolina Medical Center · Florence, SC · Full-time
13. RN Extern - Cardiac Observation PRN, Medical University of South Carolina Medical Center · Florence, SC · Part-time
14. Registered Nurse (RN) Weekend Only - Med Surg - Bon Secours St. Francis Hospital, Bon Secours Mercy Health · Charleston, SC · Full-time
15. Registered Nurse (RN) - Medical Intermediate Care/Hospitalist - Roper Hospital, Bon Secours Mercy Health · Charleston, SC · Full-time
16. Registered Nurse-Plastics/Reconstructive/Weight Loss Surgery, Spartanburg Regional Healthcare System · Spartanburg, SC · Full-time
17. Nursing Clinical Educator-Day Shift, Spartanburg Regional Healthcare System · Spartanburg, SC · Full-time
18. Staff Nurse Phase II (PRN) Cardiac Rehabilitation Seacoast, McLeod Health · Little River, SC · PRN
19. Registered Nurse - PRN (As Needed)- Home Health (Dillon County), McLeod Health · Dillon, SC · PRN
20. Labor & Delivery Registered Nurse II, Medical University of South Carolina Medical Center · Charleston, SC · Full-time